This discussion of several of Visceral Games products, Dante’s Inferno, Dead Space, and Dead Space 2 does contain major spoilers, especially in the case of the latter two games.
Work, eviscerate, work, eviscerate. Masculinity in the Dead Space universe is pretty minimally represented in a fairly stereotypical way by the aggressive (but ever handy) Isaac Clarke.
Femininity in this series, however, seems to be grotesquely and decorously painted all over the virtual walls of this and (to some degree at least) Visceral’s other recent game offering, Dante’s Inferno. That painting is composed of an awful lot of twisted flesh and bodily fluids, though.