Although the plot includes a bank robbery and brief appearances by Apache Indians and Billly the Kid, Strange Lady in Town is a largely unsensational, untraditional, anecdotal, friendly, visually pleasing, and socially progressive western rooted in the time and place of 1880 Santa Fe, New Mexico. The film opens with a horse-drawn wagon popping a wheel in the wide-open space of the Cinemascope screen while Frankie Laine croons the title tune. A black-clad woman with a parasol traipses over to some cowpokes for help and introduces herself, to their surprise, as a lady doctor from Boston. She makes herself at home and charms them immediately, as she will swoop in by personality and expertise to charm most of the citizens of her new home.
The “strange lady” is Dr. Julia Winslow Garth (Greer Garson, all class and English accent and orange hair, and reportedly beset with appendicitis during filming). Those charmed include the Catholic monk next door (Walter Hampden) who runs a hospital for the Mexicans and Indians, and a striking tomboy-ish cowgirl called Spurs (Lois Smith), who’s in love with Julia’s brother David, a charming Cavalry soldier who’s nothing but trouble. He’s played by Cameron Mitchell, who, in typical Hollywood casting, is convincing as all of that except Garson’s brother.