Seven Psychopaths and Drive have what it takes to go on to be cult favourites. They were able to use the conventions of their genre to criticize the fundamental operations of it. I bring up these movies because they’re great at doing what video games have been trying and failing to do, especially recently.
The greater the failure of the video game player, the greater the financial reward of the video game machine’s owner. More frustration, more 'death', used to mean more quarters per hour. These days, it means something else, entirely.
Darksiders offers nothing especially new in terms of teaching the player to kill, but what it it does do better than many games is teach the player to be a more efficient and effective murderer by changing up some existing mechanisms of training the player in the deadly arts. Largely, this boils down to creating some rules for murder.